Diagnostic value of the biochemical parameters in patients with empyema thoracis
Journal Title: Scholars Journal of Applied Medical Sciences - Year 2016, Vol 4, Issue 4
Abstract
Abstract: Empyema thoracis means an accumulation purulent effusion in the pleural cavity. Its incidence has gradually decreased because of the increased availability and use of antibiotics. However empyema still continues to be a significant cause of morbidity, especially in developing countries. The purpose of this study was to examine the diagnostic value of pleural effusion LDH, glucose concentration and pH in patients with purulent pleural effusion. Between November 2005 and August 2012, 20 patients with empyema thoracis admitted to Dursun Odabas Medical Center were included in the study. Patients who had developed empyema thoracis associated pulmonary resection, tuberculosis, or traumas were not included in the study. After the thoracentesis, a specimen was collected to a tube for biochemical analysis (glucose, protein and LDH). A second sample was taken into a heparinized syringe for pH analysis. Pleural aspiration was initially performed in all patients. Most patients required closed chest tube drainage. Decortication was performed, if chest tube drainage failed. There were 18 male and 2 female patients. The age of patients ranged from 2 to 67 years, with a mean age of 29.17±18.52 years. The samples of pleural effusion had had a high protein and LDH levels, but low pH and glucose levels. Pleural aspiration was found successful treatment method only in two patients (10%). Tube thoracostomy was required in 18 patients, of whom four had thoracotomy. Diagnosis of empyema thoracis can be supported by biochemical analysis of pleural effusions. Underwater seal drainage plus antibiotic therapy can cure the empyema in majority of the patients. Treatment should be started without delay if the biochemical markers are positive. Keywords: Empyema Thoracis, Biochemical Parameters, Drainage
Authors and Affiliations
Meral Ekim, Hasan Ekim
Keywords
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