DICLOFENAC INDUCED ANGIOEDEMA: A CASE REPORT

Journal Title: Asian Journal of Pharamceutical and Clinical Research - Year 2015, Vol 8, Issue 2

Abstract

 Non-steroidal anti-inflammatory drugs (NSAIDs) are one of the most commonly prescribed groups of drugs for variety of indications. However, theyare associated with many potential adverse drug reactions. The detailed information of these reactions is necessary to decrease the morbidity andmortality associated with these reactions. Angioedema can be caused by many etiological factors including drugs. The NSAID induced angioedemaoccurs infrequently but sometimes it may prove fatal if not treated promptly. The angioedema due to NSAIDs use may be caused due to increase inproduction of Leukotriene due block in cyclooxygenase pathway. The mast cells and to lesser extent basophils plays a major role in pathogenesis ofangioedema. Early recognition and discontinuation of responsible NSAIDs should be done. Treatment with corticosteroids and antihistaminic is usefulin management of angioedema. The author reports a case of a patient with angioedema in association with use of Diclofenac.Keywords: Angioedema, Diclofenac, Non-steroidal anti-inflammatory drugs, Leukotrienes.

Authors and Affiliations

Harshal Nutanrao Pise, Sudhir L. Padwal

Keywords

Related Articles

REVIEW: A RECENT REVIEW IN APPLICATIONS OF HETEROCYCLIC COMPOUNDS AS ANTIMICROBIAL AGENT

A wide development in the field of multidrug resistance in antimicrobial activity which enhance the search for development of new medicinal drugs with high potential. Schiff base heterocyclic metal complex with imine moi...

IN SILICO DOCKING ANALYSIS OF YOHIMBINE ALKALOIDS FROM CATHARANTHUS ROSEUS AGAINST DENGUE FEVER

Objective: In this docking study was performed by the active site of NS2B-NS3 protease with selected plant alkaloids derived from Catharanthus roseus. On the basis of docking results, out of the nine alkaloids yohimbine...

DEVELOPMENT AND VALIDATION OF A SIMPLE HIGH-PERFORMANCE LIQUID CHROMATOGRAPHY UV METHOD FOR THE DETERMINATION OF VINORELBINE - A CHEMOTHERAPEUTIC DRUG IN SPIKED HUMAN PLASMA

Objective: Vinorelbine (VNRB) is a chemotherapeutic drug used to treat non-small cell lung cancer and breast cancer. Literature survey reveals that there are no reverse-phase high-performance liquid chromatography (RP-HP...

THE ROLE OF HEALTH INFORMATION SYSTEM IN MATERNAL AND CHILD HEALTHCARE SERVICES

Health information system deals with any system that helps in capturing, storing, transmitting, and managing health-related information of an individual or to demonstrate the activities or organizations working within he...

THE PROTECTIVE EFFECTS OF ECHINOPS HETEROPHYLLUS AQUEOUS EXTRACT AGAINST METHOTREXATE-INDUCED HEPATOTOXICITY IN RABBITS

Objective: The aim of this study was to investigate antioxidant and hepatoprotective properties of Iraqi Echinops heterophyllus aqueous crude extract and its flavonoid fraction against methotrexate (MTX)-induced hepatoto...

Download PDF file
  • EP ID EP605610
  • DOI -
  • Views 110
  • Downloads 0

How To Cite

Harshal Nutanrao Pise, Sudhir L. Padwal (2015). DICLOFENAC INDUCED ANGIOEDEMA: A CASE REPORT. Asian Journal of Pharamceutical and Clinical Research, 8(2), 4-5. https://europub.co.uk/articles/-A-605610