Diclofenac Induced Gastritis: A Case Report
Journal Title: International Journal of Research and Review - Year 2018, Vol 5, Issue 12
Abstract
Non-steroidal anti-inflammatory drugs are extensively used as anti-inflammatory agents, antipyretics and analgesics by many patients worldwide. The evidence based mechanism of therapeutic effects of NSAIDS is due to inhibition of Cyclooxygenase (COX) enzyme. However, the chronic usage of NSAIDS will result in plethora of adverse effects which includes Gastrointestinal, renal and cardiovascular systems. A scrupulous literature search revealed that diclofenac can cause GI adverse effects, but no diclofenac associated gastritis report has been published till date. In this back drop, we describe a case of 50 year old man, developed gastritis and anaemia as an adverse event who was taking OTC medication of diclofenac for six months duration. After administration of intravenous antibiotic, intravenous Proton pump inhibitor, anti-ulcer agent and fluid therapy the patient was recovered and discharged.
Authors and Affiliations
Chandana T
Keywords
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