Dietary Restriction Initiated from Larval Stage Decreases Maximum Life Span in Drosophila melanogaster
Journal Title: IOSR Journal of Pharmacy and Biological Sciences (IOSR-JPBS) - Year 2016, Vol 11, Issue 6
Abstract
Dietary restriction (DR) is a way of hormesis which stimulates the adaptive response in various animals. This reduces free radical formation and induces turnover of biomolecules by autophagy. In Drosophila melanogaster also we found that, there is decrease in lipid peroxidation and increase in maximum life span when the adult flies are subjected to 20% and 40% DR. In this group DR was initiated after eclosion of flies, i. e. when they become adult. 40% DR was found to be more beneficial in this group. Contradictory results were found when Drosophila melanogaster was subjected to 20% and 40% DR from the larval stage. Lipid peroxidation was found to be at higher level up to 21 day of eclosion which was lowered in later period. Maximum life span was found to be reduced on 20% and 40% DR. The flies subjected to 40% DR from larval stage were found to be more affected.
Authors and Affiliations
Udugade R M, Deshmukh A A, Gajare K A3*
Keywords
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- EP ID EP387024
- DOI 10.9790/3008-1106053742
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