Differential Diagnosis of Oral Malignant and Premalignant Lesions by Exfoliative Cytology with Emphasis on Demographic Factors
Journal Title: International Journal of Medical Research Professionals - Year 2017, Vol 3, Issue 4
Abstract
Background: India alone accounts for one third of the world’s oral cancer and has a high rate of potentially malignant disease (PMD). Most of patients 60-80% presents with advance stage which leading to high morbidity and mortality in comparison to developed country. Objectives: To study the role of exfoliative cytology in diagnosis of malignant and potentially malignant lesion of oral cavity. Materials and Methods: The data was retrieved from the records of the patients who presented with various oral cavity lesions and subsequently advised for oral exfoliative cytology over a period of one year from January 2016 to December 2016 in A. H. Reginal Cancer Centre, Cuttack. Results: Total 1460 cases were encountered; out of which 865(59.24%) cases were malignant and 493(33.76% were benign. There were 102(6.98%) suspicious cases. Among malignant lesions, squamous cell carcinoma (SCC) was the only type encountered where as in benign group inflammatory lesions were most common (295=59.83%) followed by potentially malignant lesions (198=40.16%) comprising of leukoplakia 120 (60.6%) and oral sub mucous fibrosis 78 (39.39%). Males were predominantly affected in our series with M:F ratio 2.93:1.The age of the patients ranged from 19 years to 92 years, with mean age 49 years where as in malignant cases the peak incidence was observed in the age between 30 years and 70 years with mean age 52 years. History of smokeless tobacco use was predominant in this series. The cyto-histo correlation was available in 1047 cases. The sensitivity, specificity and diagnostic accuracy of OEC was 89.71%, 100%, and 91.4% respectively. Conclusion: Exfoliative cytology is a rapid, easy and cost effective test for detection and categorization of different oral lesions.
Authors and Affiliations
Sasmita Panda, Asaranti Kar, Sashibhusan Dash, Paresh Kumar Behera, Bharat Bhusan Satpathy, Sagarika Samanataray, Niranjan Rout
Keywords
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- EP ID EP546819
- DOI 10.21276/ijmrp.2017.3.4.032
- Views 76
- Downloads 0
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