Study of Zinc Level in Egyptian Cirrhotic Patients with Different Stages of Liver Cirrhosis
Journal Title: International Journal of Medical Research Professionals - Year 2018, Vol 4, Issue 6
Abstract
Background: Liver cirrhosis is a widespread disease differentiated by spread liver fibrosis and formation of nodules. During the last years, concentrations of minerals in patients with chronic hepatic disease have been investigated extensively. In fact, liver is responsible for regulation of the metabolic pathway and trace elements (TE) transport, and their bioavailability, distribution in tissue and consequent toxicity. , for magnesium, manganese, chromium, selenium and zinc in other types of chronic hepatic disease. The alterations of these trace elements were related mostly to malnutrition in hepatic disease. Zinc is one of the most important trace elements in the human body. Zinc is responsible for activation of about 300 different metallo-enzymes and metal-activated enzymes in vivo and is essential for the metabolism of nucleic acids and proteins. Methods: The work was carried out on a cluster of (60) patients with liver cirrhosis attending outpatient clinic and those admitted at the internal medicine inpatients wards. They were calcified into three groups A, B & C according to child calcification, 20 patients in each group. Full history, clinical examination and investigation were done, estimation of serum Zinc level. Results: Serum zinc level decreases with cirrhosis especially with advanced cases and have direct relation with the degree of severity of liver disease and its complications as hepatic encephalopathy, ascites, hypoalbuminemia and malnutrition. Conclusion: Zinc, is a helping element of the urea cycle enzymes, can be decreased in patients with cirrhosis, particularly if joined with malnutrition.
Authors and Affiliations
Khalil Ali Khalil, Fadia Mostafa Attia, Fawzy Attia Khalil, Ahmed Hamdey EL-Tabey, Hany Haron, Hesham Drwesh
Keywords
Related Articles
- EP ID EP532468
- DOI 10.21276/ijmrp.2018.4.6.007
- Views 62
- Downloads 0
Thigh Girth: A Predictor of Outcome in Arthroscopic Anterior Cruciate Ligament Reconstruction – A Retrospective Study
Background: The Objective of this study was to evaluate the effect of thigh circumference on rehabilitation after arthroscopic anterior cruciate ligament reconstruction. This study was conducted in a tertiary care instit...
Role of Dexamethasone in Supraclavicular Brachial Plexus Block: A Clinical Study
Background: The present study was conducted to assess the effect of dexamethasone on the onset and duration of anesthesia in low volume supraclavicular brachial plexus block. Materials & Methods: The present study was co...
A Histopathological Study of Endometrium in Abnormal Uterine Bleeding
Background: Abnormal uterine bleeding is one of the commonest conditions for which patients seek medical care. It is estimated that 9-30% of women of reproductive age suffer from menorrhagia. The prevalence increases wit...
Assessment of the Knowledge, Attitude and Management Practices of Type 1 Diabetes Mellitus among Primary School Teachers in Tabouk City, Saudi Arabia
Background: Diabetes mellitus (DM) is one of the most common chronic childhood diseases. For children, public schools are important locations for secondary prevention interventions to help them minimize their risk for co...
Incidence of Tobacco Chewing Habit and Oral Mucosal Lesions in Patients Reporting to the Hospital: A Prospective Study
Background: Tobacco is used in various forms like smoked or smokeless forms. Both carry risk of carcinoma. Consumption of tobacco or even exposure to tobacco smoke is a factor for multiple human carcinogens like lung can...