Directed self-assembly software for single cell deposition
Journal Title: International Journal of Bioprinting - Year 2017, Vol 3, Issue 2
Abstract
Laser direct-write (LDW) bioprinting methods offer a diverse set of tools to design experiments, fabricate tissue constructs and to cellular microenvironments all in a CAD/CAM manner. To date, we have just scratched the surface of the system’s potential and for LDW to be utilized to its fullest, there are many distinct hardware and software components that must be integrated and communicate seamlessly. In this perspective article, we detail the development of novel graphical user interface (GUI) software to improve LDW capability and functionality. The main modules in the control software correspond to cell transfer, microbead fabrication, and micromachining. The modules make the control of each of these features, and the management of printing programs that utilize one or more features, to be facile. The software also addresses problems related to construct scale-up, print speed, experimental conditions, and management of sensor data. The control software and possibilities for integrated sensor data are presented.
Authors and Affiliations
Samuel C. Sklare, Winona L. Richey, Benjamin T. Vinson and Douglas B. Chrisey
Keywords
Related Articles
- EP ID EP678666
- DOI -
- Views 174
- Downloads 0
Structural, mechanical and in vitro studies on pulsed laser deposition of hydroxyapatite on additive manufactured polyamide substrate
Additive manufacturing (AM) is an emerging field that merges engineering and life sciences to produce components that can effectively act as a replacement in the human body. This AM encompasses biofabrication using cells...
In vitro pre-vascularization strategies for tissue engineered constructs–Bioprinting and others
Tissue-engineered products commercially available today have been limited to thin avascular tissue such as skin and cartilage. The fabrication of thicker, more complex tissue still eludes scientists today. One reason for...
A continuous net-like eutectic structure enhances the corrosion resistance of Mg alloys
Mg alloys degrade rather rapidly in a physiological environment, although they have good biocompatibility and favorable mechanical properties. In this study, Ti was introduced into AZ61 alloy fabricated by selective lase...
Utilising inkjet printed paraffin wax for cell patterning applications
We describe a method to prepare patterned environments for eukaryotic cells by inkjet printing paraffin wax onto a substrate. This technique bypasses the requirement to create a master mould, typically required with the...
Laser-assisted bioprinting at different wavelengths and pulse durations with a metal dynamic release layer: A parametric study
For more than a decade, living cells and biomaterials (typically hydrogels) are printed via laser-assisted bioprinting. Often, a thin metal layer is applied as laser-absorbing material called dynamic release layer (DRL)....