Disorders of purines and pyrimidines metabolism in human gastrointestinal tract cancer
Journal Title: Current Issues in Pharmacy and Medical Sciences - Year 2013, Vol 26, Issue 4
Abstract
Patients with cancer of stomach, colon cancer and rectum showed an increase in the thymidine kinase, 5'–nucleotidase of adenylate, adenosine deaminase activities and a decrease in the thymidine phosphorylase activity, which can cause DNA biosynthesis and increase of proliferation. The lymphocyte 5'–nucleotidase of adenylate, adenosine deaminase activities are associated with cellular dysfunction and can be used as a biochemical tests of it.
Authors and Affiliations
Berta Borzenko, Elena Bakurova, Ksenia Mironova
Keywords
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