Disulphide Bond Reduction of RNase A by Drug Metosartan a Comparative Study
Journal Title: International Journal of Biochemistry Research & Review - Year 2017, Vol 20, Issue 1
Abstract
RNase A is the most experimental protein in the 20th century. Disulphide bonds are necessary for enzymatic action of many proteins as it is also required for this protein. RNaseA kinetic studies is performed with the drug metosartan using RNA as the substrate Metosartan, is a drug used as blocker in excretion and found to contain inhibitory property on RNaseA. Protein degradation and thiol titration assay has found to be that the drug has reducing property on RNaseA.
Authors and Affiliations
Eswari Beeram, Kamala Katepogu, Bukke Suman, Divya Bysani, Thyagaraju Kedam
Keywords
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- EP ID EP316965
- DOI 10.9734/IJBCRR/2017/37444
- Views 154
- Downloads 1
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