DIURETIC AND ANTI-INFLAMMATORY ACTIVITY OF AQUEOUS EXTRACT OF AERVA SANGUINOLENTA (L.) BLUME.
Journal Title: International Research Journal of Pharmacy (IRJP) - Year 2011, Vol 2, Issue 7
Abstract
The study was designed to evaluate the diuretic and anti-inflammatory potency of aqueous extract of whole plant of Aerva sanguinolenta in wistar albino rats. Different parameters viz. total urine volume, urine concentration of electrolytes such as sodium; potassium and chloride have been evaluated for assessment of diuretic activity. Anti-inflammatory was performed against carrageenan induced paw oedema method by using indomethacin as standard. The results revealed that the aqueous extract showed significant diuretic activity at a dose of 400 mg/kg body weigh by increasing the total volume of urine and concentration of sodium, potassium and chloride ions in urine and also extract showed significant anti-inflammatory activity.
Authors and Affiliations
K Reddy, Rajeev Reddy , S Ganapaty
Keywords
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