Does Controlled And Uncontrolled Type IIDiabetes Mellitus Affect Median Nerve Conduction Parameters? - An Analytical Study.
Journal Title: IOSR Journal of Dental and Medical Sciences (IOSR-JDMS) - Year 2018, Vol 17, Issue 4
Abstract
Background: Diabetic neuropathy is one of the most commonly occurring micro vascular complications.Glycatedhaemoglobin (HbA1c) has been established as a marker of glycemic control and it also indicates the risk of developing small vessel complications.Nerve conduction studies are useful in early evaluation in diabetic peripheral neuropathy. Therefore, this study was undertaken to assess the nerve conduction study results among known cases of type II diabetes mellitus with uncontrolled glycemic (HbA1C elevated), diabetics with controlled glycemic (HbA1C at normal level) and to compare it with non-diabetic subjects. Methods:The study was conducted in 60 male subjects in age group of 30-45 years. Subjects were subdivided into 3 groups-Group 1: 20 Type II diabetes mellitus patients with uncontrolled diabetes;Group 2:20 Type II diabetes mellitus patients with controlled diabetes; Group 3: 20 non-diabetic healthy subjects. Nerve conduction velocity, amplitude and latency of right median nerve (motor and sensory component) were recorded by computerized RMSEMG System. Results: Median nerve conduction study showed significant increase in mean latency and significant decrease in amplitude and velocity values in uncontrolled diabetics when compared with both controlled diabetic and non-diabetic group. No significant difference in mean latency, amplitude and velocity values was observed when controlled diabetic group was compared with non-diabetic group Conclusions:Electrophysiological parameters in median nerve conduction (both sensory and motor component) deteriorate both in uncontrolled and controlled type II diabetic mellitus patients as compared to non-diabetics but more significantly in uncontrolled diabetics. Monitoring of HbA1C can be taken as an index for predicting neuropathic changes in type II diabetics.
Authors and Affiliations
Dr. D. Pole, Dr. S. Kayande, Dr. A. Khare
Keywords
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- EP ID EP370801
- DOI 10.9790/0853-1704084649.
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