Does Sickle Cell Disease Protect Against Diabetes Mellitus? Cross-sectional study
Journal Title: Sultan Qaboos University Medical Journal - Year 2015, Vol 15, Issue 1
Abstract
Objectives: Te co-existence of diabetes mellitus (DM) and sickle cell disease (SCD) is rare. Tis study aimed to explore whether SCD patients have the same DM prevalence as the general population in a country with a high prevalence of DM. Methods: Tis cross-sectional study included all SCD adult patients admitted to Salmaniya Medical Complex, Bahrain, between 2003 and 2010 (n = 2,204). A random sample (n = 520) was taken to establish the prevalence of DM. Laboratory records were examined to determine the presence of DM. Results: Tere were 376 SCD patients with complete records; of these, 24 (6.4%) had DM. Te age- and sex-standardised prevalence of DM was 8.3%. Conclusion: While the prevalence of DM in SCD patients in Bahrain was high, it was lower than expected in this population. SCD may have a protective effect towards DM development. However, the impact of these two conditions on vascular diseases suggest a need for screening and aggressive treatment in this population.
Authors and Affiliations
Ali A. Mohamed| School of Medicine, Royal College of Surgeons in Ireland Medical University of Bahrain, Busaiteen, Bahrain, Fathia Al-Qurashi| Department of Haematology, Royal Albert Edward Infrmary, Wrightington, Wigan & Leigh NHS Foundation Trust, UK, David L. Whitford| Department of Family & Community Medicine
Keywords
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