DRUG DELIVERY BY NANODIAMONDS
Journal Title: International Research Journal of Pharmacy (IRJP) - Year 2011, Vol 2, Issue 4
Abstract
Nanomaterials less than 100-thousand-millionths of a meter in size have the potential to radically change current drug delivery techniques with early trials showing the ability of nanomaterials to moderate the release of highly toxic chemotherapy drugs and other therapeutics with both reduced side effects and improved targeting. A nanodiamonds application in biology and nanoscale medicine highlights how nanodiamonds have emerged in clinical and medical relevance through assisting in the processes of drug delivery, cellular interrogation and detection. These nanomaterials can shuttle chemotherapy drugs to cells without producing the negative effects of today's delivery agents. Clusters of the nanodiamonds surround the drugs to ensure that they remain separated from healthy cells until they reach the cancer cells, where they are released. More benificial part is that these nanodiamonds have been shown not to induce inflammation in cells once they have done their job. Nanodiamonds are the diamond crystals less than 100 thousands million of meter in size. Delivery of drug using this system reduces the side-effects and improves the targets.
Authors and Affiliations
Parimal Prajapati , Krunal Patel , Maulik Ganatra , Anil Solanki , Jyoti Sen
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EFFECT OF FORMULATION AND PROCESS VARIABLES ON DRUG CONTENT AND ENTRAPMENT EFFICIENCY OF ACECLOFENAC NANOSUSPENSION
The present investigation was undertaken to study the effect of polymer and surfactant concentration (formulation variables) and sonication time / agitation speed (process variables) on drug content and entrapment effici...
NOVEL INVESTIGATIONS ON THUJA OCCIDENTALIS EXTRACT ON RABBIT HEMATOLOGICAL AND BIOCHEMICAL PARAMETERS
Thuja occidentalis (family: Cupressaceae) has been used as antiseptic, expectorant, diuretic and in the treatment of cancer and removal of kidney stones in different systems of medicine. The present studies were carried...
FORMULATION AND EVALUATION OF DISPERSIBLE TABLETS OF AMOXICILLIN TRIHYDRATE AND DICLOXACILLIN SODIUM
In the present work attempts were made to prepare dispersible tablets of Amoxicillin trihydrate and Dicloxacillin sodium by direct compression technique to enhance patient compliance. The three superdisintegrents used in...
NON INVASIVE THERAPEUTIC DRUG MONITORING OF PROPRANOLOL HYDROCHLORIDE BY REVERSE IONTOPHORESIS
Therapeutic drug monitoring (TDM) is highly required for drugs possessing narrow therapeutic index as a slight variation in the therapeutic range could result in no or low clinical efficiency or causes significant side e...