Drug Utilisation Pattern of Antihypertensive Drugs
Journal Title: International Journal of Medical Science and Innovative Research (IJMSIR) - Year 2017, Vol 2, Issue 6
Abstract
Background: The antihypertensive drugs used for the management of hypertension constitute a significant portion of the medicines prescribed in a health care centres.Our study aimed to find out the most commonly prescribed antihypertensive drugs in study patients with or without other comorbidity/s. Material and Method: A Prospective observational study was carried out on 200 hypertensive patients with or without other chronic co-morbidity/s of age 20-80 years visiting outpatient department of Medicine at Maharishi Markandeswar Institute of Medical Science and Research,Haryana, India. Ethical clearance was taken prior to the start of the study and patient’s informed written consent was obtained. All the relevant data was collected from the prescription card of the patient on a preformed Performa and analyzed using descriptive statistics. Result: Total of 301 antihypertensive drugs were utilized during study period among which monotherapy(55.5%) was mostly used followed by combination therapy (39.5%). The most common group prescribed was calcium channel blocker (23.92%) and the most frequent Fixed Drug Combination as per group was ACE inhibitor + thiazide diuretic (20.23%) followed by ARB + thiazide diuretic (19.1%). Among all the antihypertensive drugs, amlodipine was the highest used (19.94%) and diabetes mellitus (28.7%) was the most recurrent co-morbidity observed in patients. Conclusion: Calcium Channel Blocker was the most common drug group and ACE inhibitor + thiazide was the most frequent FDC prescribed. Prescriptions evaluation revealed that most of the prescription were rational and were in accordance with the JNC-8 treatment guidelines.
Authors and Affiliations
Karun Bhatti
Keywords
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