Dual Role of Endophytic Fungi from the Roots of Terminalia arjuna (Roxb.) Wight & Arn

Journal Title: Journal of Pharmaceutical and Biomedical Sciences - Year 2017, Vol 7, Issue 6

Abstract

Plant endophytes constitute different crucial parts of microbial differences. Plant endophytic fungi are an imperative and novel asset of natural bioactive metabolites with their different potential applications in different industries including medicine. This article focuses on the root of Terminalia arjuna, the plant with rich ethnobotanical uses, for the nearness of endophytic organisms and to decide their antibacterial and anticancer potential from its common natural surroundings. Considering the significance of this plant based on the various research, antibacterial activity was tested against four human pathogenic microorganisms in bioactive metabolites and were subjected to different tests to decide phytochemical constituents. After the screening, MTT was performed in the crude extract. The outcomes demonstrate that the crude extract of fungal endophytes of T. arjuna have both antibacterial effects and anticancer effect when tried in MCF-7 cell line.

Authors and Affiliations

Thangaraj A, Mujeera Fathima

Keywords

Related Articles

Detarium microcarpum Stem Bark Extracts Induce Apoptosis in Human Breast Adenocarcinoma MDA MB 231 Cells via cJNK Activation and Mitochondrial Cytochrome C Release

Detarium microcarpum stem bark extract (DMSE) is one of the medicinal herbs used by the traditional medical practitioners in North East Nigeria to treat or manage various ailments such as wounds, inflammation and some fo...

A Clinical Study of Secondary Haemorrhoids and Its Management

Background Haemorrhoids are defined as the symptomatic enlargement and distal displacement of the normal anal cushions. The most common symptom of haemorrhoids is rectal bleeding associated with bowel movement. The abnor...

Personalized Medicine Phenytoin Therapy

Phenytoin is one of the antiepileptic drugs most widely prescribed. This drug has narrow therapeutic index, and often treated for a long time. Phenytoin was metabolized by CYP2C9 (major) and CYP2C19 (minor). The purpose...

Post-Cyclone Poisonings in Paediatric Age Group: An Abnormal Demography

Tropical cyclones cause substantial damage to Odisha, one of the coastal states of India, because of the geographical situation and dense population living in the coastal belts. Poor housing is the major cause of increas...

Scar Endometriosis: A Case Report

Endometriosis is defined as functioning endometrial glands and stroma outside the uterus. Pelvic endometriosis is more common than extrapelvic sites. Among extrapelvic sites, scar endometriosis is a very rare entity and...

Download PDF file
  • EP ID EP320533
  • DOI -
  • Views 100
  • Downloads 0

How To Cite

Thangaraj A, Mujeera Fathima (2017). Dual Role of Endophytic Fungi from the Roots of Terminalia arjuna (Roxb.) Wight & Arn. Journal of Pharmaceutical and Biomedical Sciences, 7(6), 220-225. https://europub.co.uk/articles/-A-320533