Dynamic Contrast Study and Diffusion Weighted Imaging with 3T Magnetic Resonance Imaging in Differentiation of Benign from Malignant Masses of Female Breast
Journal Title: INTERNATIONAL JOURNAL OF SCIENTIFIC STUDY - Year 2017, Vol 5, Issue 3
Abstract
Introduction: Breast cancer is the most common cancer in females and is the 2nd leading cause of death among female after lung cancer. Materials and Methods: Study includes 50 cases of breast masses in female came for magnetic resonance imaging (MRI) examinations between February 2015 and September 2016. MRI examination routine sequences along with dynamic contrast-enhanced (DCE) study and diffusion-weighted imaging (DWI) and the results were compared with the cytopathological examination considered as the standard diagnostic method. Results: There were 18 benign lesions and 32 malignant lesions fond in this study. DCE-MRI proved to have a sensitivity of 93.75%, and a specificity of 72.2% in diagnosing malignant pathologies. Apparent diffusion coefficient cutoff value to differentiate the benign from malignant lesions was 1.4 × 10−3 mm2/s (P < 0.001). Conclusion: The combined MRI protocol including DCE-MRI and DWI proved to be increasing the sensitivity and specificity of MRI in differentiating benign from malignant lesions.
Authors and Affiliations
Rajesh Singh, Sanjay Kumar, Ujjwala Goswami, S B S Netam, V Patre, Pratima Kujur, C D Sahu, Vishal Jain
Keywords
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