Dynamics of serum immunoglobulins at horses with different courses of uveitis
Journal Title: Бюлетень "Ветеринарна біотехнологія" - Year 2017, Vol 30, Issue
Abstract
The article presents results of the research of content of IgA, IgM and IgG in clinically healthy horses (n=10) and horses with acute, subacute and chronic uveitis (n=10). During the study feeding, maintenance and operation of horses all groups were similar. The concentration of immunoglobulins was measured by radial immunodiffusion in gel by G. Mancini et al. It is shown that the development of acute uveitis in horses associated with a significant decrease of IgA and IgG content in the blood serum in the background of increase the IgM content (disimmunoglobulinemia). Immunoglobulins content at subacute uveitis was not significantly different from that one in clinically healthy horses, with the exception of a slight decrease in the content of IgG. The chronic relapsing course of uveitis associated with a significant decrease in the authentic content of IgA and IgM at the same time reducing the apocryphal content of IgG, that is indicates on the development of disimmunoglobulinemia.
Authors and Affiliations
Andriy Mezhenskyi, Anna Kyivska
Keywords
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- EP ID EP273665
- DOI 10.31073/vet_biotech30-22
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