Early arthritis – current state of knowledge
Journal Title: Postępy Nauk Medycznych - Year 2012, Vol 25, Issue 2
Abstract
Early arthritis is often undifferentiated with various oncet (mono, oligo or polyarticular) and the duration of the symptoms less than 3 months. Most of the patients have negative rheumatoid factor (RF-IgM) and also there is no present other clinical symptoms satisfied for fulfiling classification criteria. Majority of patients with undifferentiated arthritis, in the various period of time, progress to rheumatoid arthritis (RA). In this review focuses on the importance of occurrence anti-citrullinated peptides (ACPA), they level and nature in making the diagnosis and prognosis of early arthritis, the role of Porphyromonas gingivalis infection as potential etiological factor of inflammation in RA, diffculty in clinical assessment of synovitis and inability of conventional radiography to detect early destructive changes in the joints. The differences in the sensitivity and specyficity the old (ACR 1987) and new (ACR/EULAR 2010 ) classification criteria for RA was discussed.
Authors and Affiliations
Anna Filipowicz-Sosnowska
Keywords
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