Early diagnosis of childhood Acute lymphoblastic leukemia
Journal Title: Perspectives In Medical Research - Year 2017, Vol 5, Issue 1
Abstract
Acute lymphoblastic leukemia (ALL) is characterized by an overproduction of immature white blood cells, called lymphoblasts or leukemic blasts. These cells crowd the bone marrow, preventing it from making normal blood cells. They can also spill out into the blood stream and circulate around the body. Due to their immaturity, these cells are unable to function properly to prevent or fight infection. Inadequate numbers of red cells and platelets being made by the marrow cause anemia, and easy bleeding and bruising. ALL is the most common type of childhood leukemia, and the most common childhood cancer. It is more common in males than in females. The exact causes of ALL remain largely unknown but it is thought to result from mutations in one or more of the genes that normally control blood cell development. Chemotherapy is the main form of treatment for ALL. A combination of drugs, including steroids, is usually given in several cycles with a rest period of a few weeks in between. Initially, the aim of treatment is to destroy leukemic cells and induce a remission.
Authors and Affiliations
Mahesh Kumar
Keywords
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