EAT AN ORANGE TO KEEP ANXIETY AT LONG RANGE
Journal Title: International Research Journal of Pharmacy (IRJP) - Year 2012, Vol 3, Issue 10
Abstract
Orange fruit (citrus sinensis) is a favorite fruit of all sections of the society, particularly among patients suffering from different ailments for its nutritional and medicinal properties. This study was undertaken to test the efficacy of orange juice in the management of anxiety. A total of 72 mice divided in 12 groups were employed in this study. Orange juice (2.5%, 5%, 7.5%, 10% v/v) was administered orally to mice with the help of an oral feeding needle. Elevated plus maze and light - dark model served as behavioral models in this study. Peripheral cholesterol, reduced glutathione and thiobarbituric acid levels were estimated before and after administration of orange juice. Citrus sinensis significantly increased the time spent by mice in open arm in elevated plus maze test. Furthermore, there was enhancement in the time spent by mice in lit compartment of the light - dark model. Orange juice significantly (P<0.01) increased the GSH levels of brain. On the other hand, orange juice significantly (P<0.01) decreased the TBARS and cholesterol levels. All these findings, when combined together reflect the anti-anxiety potential of orange juice.
Authors and Affiliations
Milind Parle , Dev Chaturvedi
Keywords
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