ECHOCARDIOGRAPHIC FINDINGS IN COPD AND THEIR CORRELATION TO SEVERITY OF DISEASE- AN OBSERVATIONAL STUDY FROM NORTH INDIA
Journal Title: Journal of Evolution of Medical and Dental Sciences - Year 2018, Vol 7, Issue 6
Abstract
BACKGROUND Cardiovascular disease accounts for much of mortality and morbidity in COPD, according to literature echocardiography provides a rapid, non-invasive and accurate method to evaluate cardiac function. This study was undertaken to study the echo-cardiographic findings in COPD patients and to assess their correlation to severity of COPD. MATERIALS & METHODS 50 patients who were fulfilling selection criterion were randomly selected for this prospective observational study. They underwent thorough history taking and physical examination, basic laboratory investigations, chest X ray, PFT, ECG and transthoracic echocardiography to look for PAH and cor-pulmonale. RESULTS In this study 84% of the patients were males and 16% were females. The mean age was 59.94 (±10.37) years, range 40-85 years. Majority of the patients had history of tobacco exposure of at least 20-29 pack years. 36% of the patients had clinical evidence of congestive cardiac failure. Maximum number of patients (60%) had severe airflow obstruction at the time of presentation and only 4% had mild disease. Overall, 54% of the patients in this study had echocardiographic evidence of cor-pulmonale, 56% had pulmonary hypertension, 48% had right ventricular dilatation, 28% patients had right ventricular hypertrophy, 14% of the patients had features of RV failure while 8% patients had left ventricular systolic dysfunction. PAH was seen in 68%, 43% and 25% in the severe, moderate and mild disease groups, respectively. In the severe group, 73.3%(22/30) of the patients had echo evidence of pulmonary hypertension, and 76.7%(23/30) had cor-pulmonale. Only in the severe group 23.3% of the patients had echo evidence of RV failure. Left ventricular systolic dysfunction was present in 4 patients (13.3%), all had severe COPD. CONCLUSION All the echocardiographic findings had statistically significant correlation with severity except RV hypertrophy, inter ventricular wall motion abnormality, and left ventricular systolic dysfunction. The incidence of all the echocardiographic findings increased as the severity of the disease increased. The echo signs of RV dilatation, RV failure, pulmonary hypertension, cor-pulmonale and LVDD correlated significantly with the severity of the disease (p< 0.05)
Authors and Affiliations
Shri Krishna Gautam, Brijesh Kumar, Anand Kumar Singh, Mainak Deb
Keywords
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- EP ID EP399025
- DOI 10.14260/jemds/2018/182
- Views 62
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