Effect of Adding Clonidine to Levobupivacaine in Supraclavicular Brachial Plexus Block- A Randomized, Controlled Study
Journal Title: Scholars Journal of Applied Medical Sciences - Year 2018, Vol 6, Issue 9
Abstract
Various drugs are used with local anesthetics for upper limb surgeries and postoperative analgesia. We experimented the effect of addition of clonidine with levobupivacaine in supraclavicular brachial plexus block with respect to onset & duration of sensory and motor blockade and duration of analgesia.A total of 60 patients of ASA grades I and II, aged 18-60 yrs of either sex scheduled for upper limb surgeries under supraclavicular brachial plexus block were divided into 2 equal groups in a randomized pattern. Patients in group L (n = 30), received 30 ml of 0.5% levobupivacaine with 1ml normal saline (control) and in group LC (n = 30), received 30 ml of 0.5% levobupivacaine with 1 ml (150µg) clonidine. The onset and duration of sensory and motor block & duration of analgesia were analyzed in both the groups. Statistical analysis done with SPSS 17 software and p value<0.05 taken as significant.The mean time of onset of sensory & motor blockade were 12.43±2.56 min and 17.96±3.05 min in group L and 9.03±1.60 min &15.00 ± 2.40 in group LC .The durations of sensory and motor block were 660.16 ± 44.28and 535.33 ± 50.66 min respectively in Group L, whereas they were 880.16 ± 55.48 and 771.83±54.19 min respectively in Group LC. The duration of analgesia was 728.86 ± 45.12 min in Group L compared to1013.5± 59.01 min in Group LC (p < 0.001). There was statistically significant difference present in onset and duration of sensory and motor blockade and duration of analgesia between 2 groups. Addition of clonidine in supraclavicular brachial plexus block with levobupivaicane decrease the onset of sensory and motor block and increase the duration of sensory and motor block with prolonged duration of analgesia.
Authors and Affiliations
Dr. Manish Gupta, Dr. Shikha Goyal, Dr. Neelima Tondon
Keywords
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