Effect of Aqueous Extracts of Green Tea in Arsenic induced Toxicity in Mice
Journal Title: Open Journal of Plant Science - Year 2017, Vol 2, Issue 1
Abstract
Ground water arsenic contamination is a global problem affecting thousands of people worldwide, thus present study was aimed to evaluate the hypothesis that green tea extracts, having high polyphenolic content, might be able to combat the oxidative cellular damage caused by arsenic toxicity and to prevent further development of free radicals. In the present study treatment groups received sodium arsenite orally at the dose of 3 mg kg-1 body weight daily for 4 weeks followed by administration of Camellia sinensis (green tea) 300 mg kg-1 body weight daily by gavage method for 6 weeks. Their biochemical levels like liver and kidney function tests were assayed and were found with elevated levels. Furthermore, their free radical assessment like lipid peroxidation levels were assayed which was found to be many folds higher. But, after administration of aqueous extract of green tea, there was significant amelioration in the biochemical and lipid peroxidation levels. The protective effect of these antioxidants was shown in the form of normalization of enzymatic and non-enzymatic activities represented by normalization of liver and kidney functions.
Authors and Affiliations
Fatmi Nahid, Fatima Naaz, Shahzada MZ, Sharma Shivdhar, Kumar Ranjit, Ali Mohammad
Keywords
Related Articles
- EP ID EP556620
- DOI 10.17352/ojps.000007
- Views 60
- Downloads 0
Metals from cell to environment: Connecting Metallomics with other omics
Research activities and data collection of metals present in living organisms are called as “metallomics”. In metallomics, biomolecules incorporating metal ions viz. metalloenzymes and metalloproteins, are known as “meta...
Medicinal properties of Abutilon Indicum
Abutilon Indicum is a common Indian shrub, belonging to the family Malvaceae; Also known as Mallow in english, Abutilon Indicum is used as a medicinal plant. It has been extensively used as a traditional medicine as a la...
Effect of a twin-herb formula for the Treatment of Chronic Non-healing Ulcers: a Clinical Study
Forty-four patients (27 males and 17 females) with Chronic Non-healing Ulcers that had been refractory to conventional treatment were enrolled in a single arm pre- and post-treatment clinical trial. A twin-herb formula w...
Modulation of the Activity of Enzymes Involved in Carbohydrate Metabolism during Flower Development of Grapevine (Vitis Vinifera L.)
In order to further understand the relationships between flower development and sugar metabolism in grapevine, the fluctuations of both starch and sucrose contents were compared with the activity of their related enzymes...
Varietal Screening of Early Maize Genotypes in Western Mid-Hills of Nepal
Eleven early maize (Zea mays) genotypes were evaluated for their yield and yield attributing traits at the research block of Regional Agriculture Research Station (RARS) Lumle, Kaski, Nepal during kharif season of 2016....