Effect of Cisplatin and 5-Fluorouracil on Total Protein Contents in Fresh Water Bivalve Parreysia Corrugata.
Journal Title: IJAR-Indian Journal of Applied Research - Year 2015, Vol 5, Issue 1
Abstract
Cisplatin and 5-Fluorouracil are potent and valuable anticancer drugs widely used for chemotherapy against solid tumors. These drugs exhibits effective chemoprevention in cancer therapy and also lead to several manipulations and cytotoxicity. In present toxicity studies, sub-lethal doses of cisplatin and 5-fluorouracil (LC50/10 for 96 hours) were given to an experimental model, the fresh water bivalve Parreysia corrugata for 30 days. The total protein contents were estimated from different tissues of control and treated bivalves by Lowry’s method. It was found that the total protein contents were decreased in tissues of experimental bivalves with increase in period of exposure to these anticancer drugs. It was also observed that the decrease in amount of total protein content- in tis sues was more in cisplatin treated bivalves than that of 5- fluorouracil treated bivalves.
Authors and Affiliations
Mr. Gawali R. D. , Dr. Zambare S. P
Keywords
Related Articles
- EP ID EP529129
- DOI -
- Views 61
- Downloads 0
CANADIAN FOREGIN DIRECT INVESTMENT IN INDIA
The Foreign Direct Investment means “cross border investment made by a resident in one economy in an enterprise in another economy, with the objective of establishing a lasting interest in the investee economy. FDI is al...
A MICROSCOPIC STUDY OF DEVELOPMENT IN HUMAN FETAL PANCREAS
Forty aborted human fetuses (25 male, 15 female) of 12-40 weeks gestational age with no obvious congenital abnormality were obtained with the permission of Professor and Head, Department of Obstetrics and Gynaecology of...
IMPACTS OF MORINGA DIETS ON GLYCOGEN CONTENT IN COPPER EXPOSED FISH, CYPRINUS CARPIO
Tissue glycogen content was drastically reduced in copper exposed fish as compared to control fish, even though both of them received the control diet. The decline of glycogen content was related to an extension of ex-pe...
A STUDY ON PERFORMANCE OF PRIMARY AGRICULTURAL COOPERATIVE CREDIT SOCIETIES IN THIRUVANNAMLAI DISTRICT TAMIL NADU.
RBI started special department for the development and growth of Co-operative credit Societies, farmer can get the credit from the primary agriculture credit co-operative society. These societies are working for farmer,...
Clinical spectrum of findings in deep venous thrombosis of lower limbs referred for color Doppler ultrasound.
Background: Deep venous thrombosis (DVT) of lower limbs is one of the most common cause for the majority of deaths caused by pulmonary embolism. Many medical and surgical disorders are complicated by DVT. Most venous thr...