Effect of Dexmedetomidine on Emergence Agitation after Nasal Surgeries
Journal Title: Journal of Medical Science And clinical Research - Year 2015, Vol 3, Issue 9
Abstract
Background: Emergence agitation is a short lived phenomenon occurring commonly after nasal surgery. In this study we used dexmedetomidine infusion in the intraoperative period to decrease the incidence of emergence agitation in adult patients posted for nasal surgery. Methods: 100 adult patients (ASA I-II, 20-60 years posted for nasal surgery were randomly divided into two groups. Group D received infusion of dexmedetomidine 0.4mcg/kg/hr during the intraoperative period, and Group C received normal saline infusion as placebo. All patients were induced with fentanyl (1mcg/kg) and propofol (1.5mcg/kg) and maintained with isoflurane. Incidence of agitation, hemodyanamics, pain scores, time to verbal commands and extubation were evaluated. Results: Incidence of emergence agitation was lower in Group D (26%) than Group C (50%). Group I showed more stable hemodyanamics than Group II. Time to verbal response and extubation was more prolonged for Group D than Group C (p < 0.05) though it was not clinically significant. Conclusion: The use of dexmedetomidine as intraoperative infusion resulted in smooth emergence with more stable hemodyanamics.
Authors and Affiliations
Dr Hina Khurshid
Keywords
Related Articles
- EP ID EP212371
- DOI -
- Views 67
- Downloads 0
Corelation of Sehgal Index and Rbc Indices For Screening of Beta Thalassemia Trait
Background: Hemoglobinopathies are a group of disorders of hemoglobin synthesis characterized by the absence or reduction of one or more of the globin chains of hemoglobin. Materials and Methods: This is an observational...
Red Blood Cells Morphological Changes as a Prognostic Tool for Organophosphorus Toxicity Patients
Aims & Objectives- Identify and exclude the misinterpretation of peripheral blood smears examination. Identify organophosphorus induced RBC & WBC morphological changes used as a prognostic tool. Identify the organophosph...
Primary Renal Leiomyosarcoma: A Case Report
Primary sarcomas of kidney are rare tumors, which comprise 0.8% of all renal tumors. Leiomyosarcoma account for 50-60% of kidney sarcomas; followed by liposarcomas in 10-15% of cases1 . They usually occur in the right ki...
Role of Serum C-Reactive Protein Levels in Diagnosis of Acute Appendicitis
Background: Appendectomy is one of the most common surgical emergencies. Despite of manyadvances in biochemical and radiological investigations, rate of negative appendectomy [histopathology negative] is considerably hig...
Impact of Chemoradiation on Lung Function in Breast Cancer Survivours
Introduction: Both earlier diagnoses of the breast cancer and novel chemo radiation therapy strategies have resulted in a considerable improvement in breast cancer survival. This study was intended to assess the long ter...