Effect of duration of phototherapy on serum calcium level in newborn with Neonatal Jaundice
Journal Title: Pediatric Review: International Journal of Pediatric Research - Year 2014, Vol 1, Issue 3
Abstract
Introduction: Hyperbilirubinemia (jaundice) is a common and in most cases, benign problem in neonates. Treatment options available for neonatal jaundice are phototherapy, exchange transfusion and pharmacological therapy. Hypocalcaemia is one of the know side effects of phototherapy. Objective: Effect of duration of phototherapy on serum calcium level in newborn with neonatal jaundice. Methods: Design: A prospective study Setting: A tertiary care center of Karnataka (SIMS, Shivamogga). Participants: 100 full term and 100 preterm neonates with gestational age between 34 to 42 weeks were included in study. Main outcome measures: Blood was drawn from these neonates to measure serum bilirubin and serum calcium at the time of initiation of phototherapy (0 hours) and at 24, 36, 48 hours of phototherapy. Results: Incidence was 48% in preterm and 14% in term neonates. Incidence of hypocalcaemia according to duration of phototherapy being, 2 out of 24 (8%) at 24hrs of PT, 15 out of 73 (21%) at 36 hrs of PT, 45out of 103 (44%) at 48hrs of phototherapy. Out of which incidence was more in preterm than in term neonates, more in SGA neonates then AGA. Incidence is not affected by sex of newborn and mode of delivery and parity of mother. Conclusion: These values show that incidence of hypocalcaemia is a significant side effect of phototherapy and more being in preterm and SGA neonates. So while starting phototherapy for neonatal jaundice, one need to be cautious about serum calcium status.
Authors and Affiliations
Chandrashekar B
Keywords
Related Articles
- EP ID EP322063
- DOI 10.17511/ijpr.2014.3.06
- Views 176
- Downloads 0
Etiological study of seizures among paediatric age group (1-18 years) in tertiary care medical college hospital
Introduction: Seizure is a common problem evaluated in paediatric emergency departments. A seizure or convulsion is a paroxysmal, time limited change in motor activity and/or behaviour that results from abnormal electric...
Cardiac rhythm abnormalities after transcatheter device closure of perimembraneous ventricular septal defects in pediatric patients at intermediate term follow up
Background: Transcatheter closure of perimembranous ventricular septal defects in pediatric patients poses special challenges owing to anatomical relationship between conduction system and perimembraneous ventricular sep...
Clinical profile of ascites in children at tertiary care hospital, North Karnataka
Introduction: Ascites is a common clinical problem in children with liver and renal disease. The peripheral arterial vasodilation hypothesis is mostly accepted as the patho-physiological basis of ascites. The most import...
Comparative study of the outcome of pediatric subacute sclerosing pan-encephalitis patients treated with oral ribavirin versus intraventricular interferon alpha 2b via Ommaya reservoir
Introduction: Subacute sclerosing pan-encephalitis is a childhood disease occurring after a latent period of 2–12 years due to persistent defective measles virus within the neurons and glial cells. Various drugs have bee...
Comorbidity & socioeconomic status associated with attention deficit hyperactive disorder
Aims & Objectives: (1) To find out the prevalence of ADHD in urban primary school children (2)To find out the presence of any co-morbid disorders associated with ADHD. Settings and design: This is a cross sectional study...