Effect of Epidural Nalbuphine versus Butorphanol for Postoperative Analgesia in Combined Spinal Epidural Anaesthesia (CSEA) Technique in Abdominal Hysterectomy- A Comparative Study
Journal Title: IOSR Journal of Dental and Medical Sciences (IOSR-JDMS) - Year 2019, Vol 18, Issue 3
Abstract
Background:-Postoperative pain management is important for early mobilization and post-operative discharge. The aim of the study was to evaluate the efficacy of 1 mg of epidural butorphanol with 5mg of epidural nalbuphine for postoperative analgesia following CSEA in patients undergoing abdominal hysterectomy. Methods: Sixty patients undergoing total abdominal hysterectomy were allocated into two groups: Group 1(n=30):received 12.5 mg of 0.5% of bupivacaine(heavy) in L3-4 intrathecally plus butorphanol 1 mg diluted in 10 ml normal saline in L2-3 epidurally. Group 2(n=30): received 12.5 mg of 0.5% of bupivacaine(heavy) in L3-4 intrathecally plus nalbuphine 5 mg diluted in 10 ml normal saline L2-3 epidurally. The duration of analgesia was recorded as the interval from the completion of anaesthetic procedure to the time of the first complaint of pain or visual analogue pain >4. Results: Higher sensory block level was attained with the nalbuphine group- T4 in 80% patients. It also showed prolonged post–operative analgesia (279.4 ± 68.43 min) compared to butorphanol group, where the time to first rescue analgesic was 201.9 ± 62.31 min.(p<0.001).The total amount of rescue analgesic consumed in the first 24 hours was significantly more in butorphanol group than the nalbuphine group(p<0.001). Conclusion: Epidural nalbuphine provided good intraoperative analgesia, prolonged postoperative analgesia, superior sedation level and stable cardio-respiratory parameters without significant adverse effects.
Authors and Affiliations
Dr. Bachaspatimayum Jayalaxmi, Dr. Nongthombam Ratan Singh, Dr. Laithangbam Pradipkumar Singh, Dr. Ajoy Pal, Dr. Niladri Ranjan Debnath, Dr. Joseph Lalhruaitluanga
Keywords
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- EP ID EP558012
- DOI 10.9790/0853-1803153944.
- Views 63
- Downloads 0
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