EFFECT OF EREMOMASTAX SPECIOSA ON EXPERIMANTAL DIARRHOEA
Journal Title: African Journal of Traditional, Complementary and Alternative Medicines - Year 2006, Vol 3, Issue 1
Abstract
This study investigated the anti diarrhoeal activity of the aqueous extract of dried ground leaves of Eremomastax speciosa (Hochst.) Acanthaceae. Diarrhea was induced in mice by the administration of 0.2 ml of castor oil, with the control group receiving water. The administration by oral garvage of 400 or 800 mg/kg body weight of Eremomastax speciosa extract reduced castor oil induced diarrheoa by reducing the number of wet stools by 42.50 and 48.35% respectively. This was as a result of the ability of the extract to stimulate the reabsorption of water from the intestinal lumen as well as significantly reducing the intestinal transit time and intestinal motility. This antidiarrhoeal property could be as a result of the tannins and flavonoids, which were found to be present in Eremomastax speciosa.
Authors and Affiliations
Julius Oben, Sheila Assi, Gabriel Agbor, David Musoro
Keywords
Related Articles
- EP ID EP101914
- DOI -
- Views 121
- Downloads 0
Antitrichomonal activity of 1,3-diaryl-2-propen-1-ones on <i>trichomonas gallinae</i>
1,3-diaryl-2-propen-1-ones were synthesized by the Claisen - Schmidt condensation method. T. gallinae parasites isolated from domestic pigeon were cultured in vitro. The in vitro susceptibility of T. gallinae was evaluat...
Gossypol content on leaves and seeds from some wild <i>malvaceae</i> species
Ten Malvaceae species were analysed for their seed and leaf gossypol content by HPLC. The results showed that gossypol is common in most of the Malvaceae family, but its concentration varies among the species and also am...
Toxicity potentials of <i>senna podocarpa</i> (guill.et perr.) lock pods in rodents
The effects of acute (LD50) and sub-chronic doses of the aqueous infusion of [i]Senna podocarpa[/i] (Guill. et Perr.) Lock pod on the liver, kidney, brain and testis of mice and rats were studied, respectively. The acute...
Toxicity of erythrophleum guineense stem-bark: role of alkaloidal fraction
The effect of the in vivo administration of the total alkaloidal fractions of the stem-bark of the Erythropleum guineense on certain biological parameters of Sprague-Dawley rats was investigated. The results revealed tha...
Acute toxicitty and sleep-wake eeg analysis of <i>stachtarpheta cayennensis</i> (verbenaceae) in rodents
This study was carried out in order to establish the scientific basis of the reported ethno-medicinal use of [i]Stachytarpheta cayennensis[/i] (Verbanaceae) as sedative drug. The acute toxicity and barbituric-hypnotic te...