Effect of Ethanolic Extract of Leaf of Piper Betle Linn as Immunomodulatory Agent: A Unique Role of Phytochemicals.
Journal Title: Journal of Biomedical and Pharmaceutical Research - Year 2013, Vol 2, Issue 1
Abstract
Background: Biochemical and immunological effect of leaf of Piper betle Linn in rat were studied. Objective: To evaluate the immunomodulatory effect of leaf of Piper betle Linn. Methods: Ethanolic EXTRACT OF LEAF OF Piper betle Linn were administered at doses of 150 and 250 mg/kg body weight for 30 days in wistar albino rats. Immunomodulatory changes and biochemical correlations were investigated. Results: Ethanolic extract of leaf of Piper betle I Linn showed increased antibody production in a dose dependent manner. It enhances the production of RBC, WBC and HB. Conclusion: Ethanolic extract of leaf of Piper betle Linn has positive immunomodulatory activities.
Authors and Affiliations
Biswajit Majumdar*| Professor and HOD, Department of Biochemistry, Gandaki Medical College, Tribhuvan University, Nepal., Md. Nazrul Islam| Professor, Department of Physiology, Chitwan Medical College, Tribhuvan University, Nepal.
Keywords
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