Effect of Fytolan on Haematology and Serum Parameters of Male Albino Rats
Journal Title: International Journal of Pharma Research and Health Sciences - Year 2014, Vol 2, Issue 4
Abstract
The present study was designed to evaluate the possible adverse effects of fytolan on the haematology and serum parameters of male albino rat. The tested doses were given orally to the wistar rats for 30 days at the dose level 5 mg, 7.5 mg and 10 mg/kg. b.wt./day. In the present investigation a significant decrease in total erythrocyte count, haemoglobin content and haematocrit value were observed, however increase in the total leukocyte count was noticed. The level of blood sugar and blood urea was increased significantly when exposed to fytolan. Protein content was found to be increased significantly after oral administration of fytolan. Significant increases in triglyceride and phospholipid level were noticed in higher doses exposed rats. In serum, total cholesterol, HDL, LDL and VLDL cholesterol were found to be significantly elevated compared to control.
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