Effect of Haematogenous oxidation therapy with Ultraviolet-C irridation in an alloxan-induced diabetes and a Poloxamer 407-induced Hyperlipidemia in rabbits
Journal Title: Journal of Diabetes and Obesity - Year 2018, Vol 5, Issue 1
Abstract
Background Recently diabetes and hyperlipidemia HL considered a major source of mortality Chemical treatments could minimize the symptoms but still the disease exists Previously Ultraviolet was usedfor treatment of ailments related to infection and metabolism Methods The studyevaluates the effects of Haematogenous Oxidation Therapy HOT on the blood when a low dose of Ultraviolet-C UV-C is directly irradiated to the blood in a diabetic rabbit model and to evaluate the effects of treatment on diabetic rabbit Type 1 Diabetes and hyperlipidemia were induced by intravenous injection of alloxan monohydrate and subcutaneous injection of poloxamer 407 respectively A 10 ml blood was collected from diabetic rabbits blood was being perfused with oxygen for 10 seconds and UV-C was irradiated to the blood UV-irradiated blood was transfused back to the original rabbits The HOT treatment was performed a total of 10 times It wasevaluated the effects of the HOT treatment on diabetes and HL through hematological and biochemical analyses before and after HOT treatment were performed Results Theresults indicated that the reduced body weight was increased and blood glucose levels were significantly reduced after the HOT treatment was performed when compared to those prior to the HOT treatment In addition CRE BUN and UA levels indicating renal functions were significantly reduced when compared to those prior to the HOT treatment When the HOT treatment was performed in a diabetic and HL rabbit model our results indicate that blood glucose levels and lipids profile were improved Conclusions Biochemical and Hematological analyswas demonstrate that the HOT was effective to alleviate diabetes and HL
Authors and Affiliations
Gareeballah Adam
Keywords
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- EP ID EP418292
- DOI 10.15436/2376-0494.18.1930
- Views 87
- Downloads 0
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