Effect of High-Intensity Interval Training (HIIT) on the Levels of Irisin and Interleukin-10 in Overweight Men
Journal Title: مجله علمی- پژوهشی دانشگاه علوم پزشکی قم - Year 2018, Vol 12, Issue 2
Abstract
Background and Objectives: Irisin hormone is released from muscle cells by exercise and exerts its positive effects through increasing energy expenditure, and considering the anti-inflammatory effect of Interleukin (IL)-10 in response to systemic inflammation, this research eas performed with the purpose of determining the effect of one period of High-Intensity Interval Training (HIIT) on serum levels of irisin and IL-10 in overweight men. Methods: In this experimental study, 20 men in the age range of (35-45 year) with body mass index of (25-30kg/m2), were selected and randomly divided into two equal groups of control and exercises. The exercise group carried out HIIT training for 6 weeks. At baseline and the end of the study, blood sampling and serum preparation were performed and the levels of irisin hormone and IL-10, were measured by ELISA method. The data were analyzed by Kolmogorov - Smirnov and t-tests at the significance level of p<0.05. Results: IL-10 serum level showed a significant increase in the of post-test in the exercise group (p<0.001). While, there was no difference between the two groups in the pre-test. Despite a little increase in the irisin level in the post-test of exercise group, the difference was not statistically significant. Also, intra-group comparison of pre-test and post-test of eacg group, only in the post-test IL-10 of the training group, the results were significant (p>0.05). Conclusion: It seems that 6 weeks of HIIT training has a positive effect on anti-inflammatory factors, especially IL-10 level in overweight men, while, it has less effect on the level of irisin hormone in these subjects.
Authors and Affiliations
Hasan Hasan, Hojatallah Hojatallah, Mohsen Mohsen, Shima Shima, Hossein Hossein
Keywords
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- EP ID EP467998
- DOI 10.29252/qums.12.2.35
- Views 64
- Downloads 0
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