Effect of Honey Intake on Liver Enzymes and Functions
Journal Title: The Journal of Middle East and North Africa Sciences - Year 2018, Vol 4, Issue 8
Abstract
Background and Objective: honey is consumed both as food and medicine. It is used as alternative medicine to treat burns, cuts, and abscesses in ancient time. It suffered a setback in modern medicine as alternative medicine as it lacked systematic scientific studies. It gained acceptance following its effectiveness where conventional treatments failed. There is a paucity of reports on the effect of honey on liver enzymes and functions. This is aimed at investigating the effect of honey on liver enzymes and function. Methodology: The animals were separated into 4 groups (n=5). Groups 1 and 2 served as control and were fed with normal rat chow and water. Groups 3 and 4 served as test groups and were fed with rat chow, water, and honey. The animals were sacrificed at the end of 20 weeks. Sera from groups 1and 3 were collected for enzymes determination while bile from groups 2 and 4 was collected after laparotomy and common bile duct cannulation under anesthesia for biochemical analyses. Results: showed that honey has no significant effects on liver enzymes and bile bilirubin levels (P>0.05). Bile secretion rate was significantly reduced in the test compared with control (P<0.05). Bile Na+, HCO3- were not significantly different while bile K+, CL-were significantly reduced in the test compared with control (P<0.05). Bile cholesterol was significantly increased in the test compared with control(P<0.05) while plasma cholesterol was significantly reduced in the test compared with control(P<0.05). Conclusion: It is therefore concluded that honey did not affect liver enzymes concentration, decreased rate of bile secretion, reduced bile potassium and chloride excretion, increased bile cholesterol excretion and reduced plasma cholesterol level.
Authors and Affiliations
E. A. Alagwu, A. S. EZEKWE, E. E. Ngwu, N. D. Alagwu
Keywords
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