Resolution of Seizures in A Child with Dravet Syndrome and Immunoglobulin G Subclasses Deficiency Treated with Valproic Acid, Intravenous Immunoglobulin, and Vagal Nerve Stimulator
Journal Title: The Journal of Middle East and North Africa Sciences - Year 2016, Vol 2, Issue 6
Abstract
Severe myoclonic epilepsy in infants, also known as Dravet syndrome, is a rare refractory form of epilepsy and its control requires a combination of several antiepileptic drugs. We describe a child who had Dravet syndrome unresponsive to a combination of drugs. Work-up for repeated infections revealed immunoglobulin G subclasses deficiency. Administration of intravenous immunoglobulin in addition to valproic acid did not control epilepsy but followed by Vagal Nerve Stimulator, resolution of seizures was sustained.
Authors and Affiliations
Dana Hasbini, Ahmad Mansour
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