Effect Of Hordeum vulgar L. on cerebellum cortex development in diabetic Albino mice fetal
Journal Title: International Journal of Farming and Allied Sciences - Year 2013, Vol 2, Issue 19
Abstract
Diabetes is one of the chronic diseases which its association with pregnancy can cause several complications for mother and fetus such as abnormal development of embryonic tissues.Common medicine for diabetes are not usable due to many side effects during pregnancy . Considering numerous studies indicating hypoglycemic effects of barley and its treatment role in diabetes . Hence, we examined the effects of barley on cerebral cortex development of diabetic mice embryos . In this study , 60 healthy female rats were used and randomly separated in to four groups . Diabetes was induced in 2 groups ,by intraperitoneal injection of streptozotocin. After getting pregnant by natural mating in each 4 group and appointing the zero day of pregnancy , they have been under treatment with barley according to groupings. On the 21 th day of pregnancy embryos have been taken out surgically of mother’s body after anesthetizing and by fixing in Formalin sampling was done from their cerebrum for making tissue slides .Microscopic analysis of tissue samples indicated that the rate of differentiation in different parts of embryonic cerebellum cortex was greater in diabetic groups treated with barley than other diabetic groups .Overall results were indicating that intake of barley seeds were effective in promoting the dilatory development process of embryonic cerebellum cortex affected by diabetic mothers.
Authors and Affiliations
Haleh Mokabber, Mehrangiz Sadooghi, Mohammad Bagher Minaee
Keywords
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