EFFECT OF HYDROLYZED RICE FORMULA ON INTESTINAL STRUCTURE OF BALB/C MICE IMMUNIZED WITH COW’S MILK PROTEINS
Journal Title: International Journal of Pharmacy and Pharmaceutical Sciences - Year 2014, Vol 6, Issue 9
Abstract
Objective: In the last few years a new preparation with hydrolyzed rice proteins was introduced and marketed as a useful alternative in the cases of cow's milk allergy.The objective of our work is to study the consequences of hydrolyzed rice formula on the structure of the intestinal epithelium.Methods: For the histological study, we have used 4 weeks old 60 female mice Balb/c, weighting (19.50 ± 0.25) g and distributed as follow:  § Group 1A: 10 mice receiving hydrolyzed rice formula for a period of 28 days after being immunized with native ß-Lg.§ Group 1B: 10 mice continue receiving a standard feed for a period of 28 days after being immunized with native ß-Lg (Positive control).§ Group 2C: 10 mice receiving hydrolyzed rice formula for a period of 28 days after being immunized with α-La protein.§ Group 2D: 10 mice continue receiving a standard feed for a period of 28 days after being immunized with α-La protein (Positive control).§ Group 3: 20 mice receiving just a standard feed with no treatment (Negative control).Results: The weight growth of all the experimental groups increases gradually with time, but the consumption of the hydrolyzed rice proteins causes a decrease of the degree of evolution of the physical weight to mice fed with this infantile formula compared with control groups. It also causes an increase of the intestinal villi height at the structure level of the intestinal mucous membrane of mice fed with hydrolyzed rice proteins compared to the positive control groups. The lymphocytic infiltration of mice fed with hydrolyzed rice proteins is similar to the one in negative control group.Conclusion: The preliminary results show that the hydrolyzed rice formula is a possible alternative to the cow’s milk formula in case of allergy. Further studies are needed to prove its nutritional efficacy.Â
Authors and Affiliations
Amina Cherifa Brahim, Samia Addou, Amel Merzouk, Omar KhÉroua, Djamel Saidi
Keywords
Related Articles
- EP ID EP579593
- DOI -
- Views 66
- Downloads 0
PREPARATION AND EVALUATION OF RAPIDLY DISSOLVING TABLETS OF RALOXIFENE HYDROCHLORIDE BY TERNARY SYSTEM FORMATION
Objectives: Enhancing the dissolution rate of raloxifene hydrochloride for the preparation of rapidly disintegrating tablets with subsequent rapid dissolution.Methods: Binary and ternary solid dispersions (SDs) with diff...
COMPARATIV EEFFECTS OF SPIRONOLACTONE AND COMBINATION WITH FUROSEMIDE OF ASCITES FLUID AND BLOOD ELECTROLYTE IN CIRRHOSIS
Objective: This study was to compare the effects of spironolactone and combination with furosemide on blood electrolyte levels and ascites fluid in patients with cirrhosis. [G1]Â Methods: This research was undertaken wit...
HEALING POTENCY OF HAEMATOCOCCUS PLUVIALIS EXTRACT FOR TREATING TYPE 2 DIABETES IN RATS
Objective: The present study aims to evaluate the antidiabetic effect of ethanolic extract of Haematococcus pluvialis (H. pluvialis) in streptozotocin (STZ)-induced diabetic rats.Methods: The antidiabetic activity of H....
EXPERIMENTAL EVIDENCES FOR THE PROMISING HERAPEUTIC ROLE OF VITIS VINIFERA SEED EXTRACT AGAINST NONALCOHOLIC STEATOHEPATITIS
Objective: The present study was planned to investigate the possible therapeutic effect of methanolic extract of Vitis vinifera seeds on high fat diet-induced nonalcoholic steatohepatitis (NASH) in forty adult female Wis...
MINERAL CONTENT OF SOME EDIBLE MEDICINALLY IMPORTANT LEAFY VEGETABLES OF KAMRUP DISTRICT OF ASSAM, INDIA
Objective: The aim of the present study was to determine the mineral components of Amaranthus spinosus, Oxalis corniculata, Bacopa monnieri, Paedaria foetida and Centella asiatica.Methods: Mineral compositions of the fiv...