Effect of Hypothyroid State on Bone Metabolism and Renal Handling of Biochemical Parameters
Journal Title: Scholars Academic Journal of Biosciences - Year 2015, Vol 3, Issue 2
Abstract
Abstract: Thyroid hormones (TH) are essential for a proper growth and development of the kidney. Hypothyroidism is one of the most common thyroid dysfunction causing remarkable changes in glomerular and tubular functions and electrolyte and water homeostasis. Hypothyroidism is found to be associated with decreased glomerular filtration, hyponatremia, and an alteration of the ability for water excretion. In turn, renal disease leads to significant changes in thyroid function. The present study was done to see the effects of hypothyroid state on body. This case-control study included total of 35 females and 15 males in the age group of 19-45years. The results were compared with 50 age and sex matched healthy controls. Patients suffering from hepatic disorders, renal disease, hyperthyroidism, any chronic illness and pregnant females were excluded from the study. All routine renal parameters were estimated in serum samples of these 50 newly diagnosed patients of hypothyroidism. The patients of hypothyroidism were found to be suffering from hyponatremia 68%, hypokalemia 37% and hypocalcemia 71%. It was also observed that the levels of urea, magnesium and creatinine were raised significantly as compared to controls. It was concluded that hypothyroid state is associated with marked derarrangements in biochemical as well as various endocrine and bone metabolic parameters. Therefore, regular monitoring of these parameters is important in patients of hypothyroidism. Keywords: Thyroid Hormones, Hypothyroidism, Hyponatermia, Hypokalemia, Hypocalcemia.
Authors and Affiliations
Isha Malik, Ashuma Sachdeva, Veena S Ghalaut, Jayeeta Badra, Lata Sangwan
Keywords
Related Articles
- EP ID EP378299
- DOI -
- Views 72
- Downloads 0
Extensive Intraductal Component (EIC) Positive Carcinoma of Breast-Four Years’ Experience at a Cancer Centre
Abstract:Extensive intraductal component positive carcinoma (EICPC) of breast is a well defined entity. Nevertheless few data exist concerning their characteristics and prognostic behaviour. Our objective was to describ...
Acute Toxic Impacts of Three Heavy Metals (Copper, Zinc and Cadmium) on Ceriodaphnia reticulata (Cladocera)
Ceriodaphnia reticulata (Cladocera: Daphniidae) is a common limnetic species in summer-temperate and tropical water bodies. In this study, that performed acute toxicity tests of three heavy metals, copper (Cu), zinc (Zn)...
Effect of varying glycated hemoglobin level on lipid profile in patients with type 2 diabetes
Chronic hyperglycemia in diabetic patients is often associated with long term complications like diabetic nephropathy, neuropathy, retinopathy and heart diseases. An abnormal lipid level is considered as the most common...
Extraction yield and antiooxidant activity of biomolecule and bioactive fractions from seed and peel parts of Pithecellobium jiringa
Abstract: Pithecellobium jiringa, known as jengkol in Indonesia, is a tropical plant of the Leguminosae family in Southeast Asia regions. P. jiringa seed has been used in Indonesian typical culinary due to its high nutri...
Effect of Metal Ions on Antibacterial Activity of Aloe Barbadensis Mill. & Coriandrum Sativum Against Various Pathogens
The present study is carried out by evaluation of antibacterial activity of Aloevera and Coriander plant samples against 3 bacterial pathogens (E.coli, P.aeruginosa and S.aureus). In this work the activity was checked in...