“Effect of in- vitro Fertilization procedure on fetal developmentA Review”
Journal Title: IOSR Journal of Dental and Medical Sciences (IOSR-JDMS) - Year 2017, Vol 16, Issue 12
Abstract
Assisted reproductive technologies are now widely used in the treatment of infertility. Popular ones are the IUI, IVF, GIFT and ICSI. Most of the studies have shown the increased incidence of developmental disorders in babies born as a result of these techniques (IVF and ICSI ). The percentage of children born after IVF will continue to increase due to demographic changes such as increasing maternal age and new developments in assisted reproduction techniques. IVF conceptions may carry an increased risk for all malformations and for certain types of defect, such as cardiovascular, musculoskeletal and neural tube defects. But few studies have asked whether this increased risk is a result of the reproductive technologies used — which involve hormone treatments and potentially harmful manipulations of sperm and egg — or pre-existing biological factors, such as genetic mutations, that may underlie a couple’s infertility. There are conflicting results for both the factors. Through this review study, we have tried to correlate the occurrence of congenital fetal anomaly with IVF techniques. Thus, by going through the various studies, we concluded that though the parental infertility factors and genetic defects are responsible but to some extent the technical defects underlying the procedures (more for ICSI than IVF) are also responsible for such congenital anomalies.
Authors and Affiliations
Mumal Nagwani
Keywords
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- EP ID EP251454
- DOI 10.9790/0853-1612092123
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