Effect of infliximab on metabolic disorders induced by Walker-256 tumor in rats.
Journal Title: Pharmacological Reports - Year 2013, Vol 65, Issue 4
Abstract
The purpose of this study was to investigate the effect of infliximab, an anti-tumor necrosis factor α (TNFα) monoclonal antibody, on the progression of cachexia and several metabolic parameters affected by the Walker-256 tumor in rats.
Authors and Affiliations
Daniele Miksza, Camila de Souza, Hely de Morais, Aline da Rocha, Gláucia Borba-Murad, Roberto Bazotte, Helenir de Souza
Keywords
Related Articles
- EP ID EP152028
- DOI -
- Views 74
- Downloads 0
Effect of cypermethrin on memory, movement activity and co-ordination in mice after transient incomplete cerebral ischemia.
Cypermethrin is a synthetic pyrethroid widely used as an insecticide. The aim of the present study was to investigate the possible effect of 0.1 LD(50) of cypermethrin on memory, movement activity and co-ordination in mi...
Anti-hypertensive effects of probenecid via inhibition of the α-adrenergic receptor.
Probenecid has long been used in the treatment of gout. Its anti-gout mechanisms consist of uric acid reuptake inhibition and the consequent facilitation of uric acid excretion. In the present study, we investigated whet...
Differential effects of glycine on the anticonvulsant activity of D-cycloserine and L-701,324 in mice.
The anticonvulsant effects of D-cycloserine, which is a partial agonist of the glycine/N-methyl-D-aspartate (NMDA) receptor, and L-701,324, which is a selective and potent antagonist that acts at the glycine site, were s...
Role of vinpocetine in cerebrovascular diseases.
A cerebrovascular accident, or stroke, is defined as the abrupt onset of a neurological deficit, which can be due to ischemia. Cerebral ischemia is caused by a reduction in blood flow that thereby decreases cerebral meta...
Influence of long-term treatment with tuftsin analogue TP-7 on the anxiety-phobic states and body weight.
TP-7 is a synthetic analogue of tuftsin. It has a structure of tuftsin, to which three natural L-amino-acids Pro-Gly-Pro are attached. This heptapeptide improves learning and memorization and causes antidepressant and an...