Effect of Intrathecal Dexmedetomidine on Shivering in Patients Undergoing Transurethral Resection of the Prostate Surgery under Subarachnoid Block
Journal Title: INTERNATIONAL JOURNAL OF SCIENTIFIC STUDY - Year 2017, Vol 5, Issue 1
Abstract
Background: Shivering is a frequent complication of urological procedures done under regional anesthesia, especially in transurethral resection of the prostate (TURP) because of absorption of large volume of irrigating fluids. Various adjuncts have been used with local anaethetics in spinal anesthesia to decrease the incidence of shivering among which dexmedetomidine has promising results. Aim: To compare the efficacy of dexmedetomidine and fentanyl on intraoperative shivering and post-operative analgesia in patients undergoing TURP surgeries under subarachnoid blockade (SAB). Materials and Methods: This prospective, randomized double-blind study included 60 patients undergoing elective TURP surgeries under SAB and were allocated into two groups: Group F - injection bupivacaine 2 ml 0.5% (10 mg) with 25 μg of fentanyl (0.5 ml) and Group D - injection bupivacaine 2 ml 0.5% (10 mg) with 5 μg of dexmedetomidine totally made to 2.5 ml. Hemodynamic parameters, shivering score, degree of sedation, and any adverse effects were recorded. Results: The shivering score was less and the time taken for rescue analgesia was more in group D than group F. Bradycardia was observed three patients (7.5%) in group D which was statistically insignificant (P = 0.241), whereas no patients had bradycardia in group F. Incidence of hypotension was similar in both groups and statistically insignificant (23 in group F versus 24 in group D [P = 0.820]). One more finding was observed that the incidence of sedation was more in group D which was statistically significant (P <0.0001). Conclusion: To conclude the use of 5 μg of dexmedetomidine to bupivacaine intrathecally is more effective in controlling shivering than fentanyl and also prolongs the duration of post-operative analgesia.
Authors and Affiliations
S Bhuvana
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