EFFECT OF ORAL AND INTRATHECAL CLONIDINE ON SPINAL ANAESTHESIA.
Journal Title: International Journal of Advanced Research (IJAR) - Year 2019, Vol 7, Issue 8
Abstract
Objectives:To compare the effects of oral and intrathecal clonidine on spinal anaesthesia with 0.5% hyperbaric bupivacaine Method: 92 patients posted for elective lower limb orthopaedic surgeries were included in this study. They were randomly divided into 3 groups, 30 patients received oral clonidine 2.5 mcg/kg prior to spinal anaesthesia with3cc of 0.5 % hyperbaric bupivacaine, 31 patients were given 75mcg of clonidine intrathecally with 3cc of 0.5% hyperbaric bupivacaine and 31 patients received plain 3 cc of 0.5 % hyperbaric bupivacaine. Results: The age and weight distribution were similar in the three groups. The onset of sensory and motor blockade was seen to occur earlier in the intrathecal group compared to the other two groups. The degree of sedation was higher among the group that received oral clonidine. There was a statistical significance among the three groups with respect to postoperative analgesia with the intrathecal group having the longest duration. There was no statistical significance among the three groups with respect to the pulse rate and blood pressure and adverse effects. Conclusion: The addition of 75mcg clonidine intrathecally to 0.5 % hyperbaric bupivacaine for spinal anaesthesia provides better postoperative analgesia, earlier onset of sensory and motor blockade and less sedation as compared to oral clonidine, with both groups demonstrating similar haemodynamic profiles.
Authors and Affiliations
Anjali Teresa Mathew Ollapally, Prithi Jain.
Keywords
Related Articles
- EP ID EP634224
- DOI 10.21474/IJAR01/9582
- Views 81
- Downloads 0
ASSESSMENT OF HAEMATOLOGICAL INDICES AND DNA PATTERN IN LEUKAEMIA PATIENTS KADUNA NIGERIA.
Leukaemia is the general name given to a group of cancers that develop in the bone marrow. It originates in developing blood cells that have undergone a malignant change leading to multiple uncontrolled malfunctioning ce...
CHEMOPREVENTION OF LUNG CARCINOGENESIS IN STRAIN BALB/C MICE WITH POLYPHENOLS OF MAHKOTA DEWA (PHALERIA MACROCARPA) FROM INDONESIAN HERBAL.
Backgroud and objective: Polyphenols of Mahkota Dewa (Phaleria macrocarpa) has potential as anticancer that is expected to inhibit lung carcinogenesis, but it has not been widely studied. This study aims to prove the rol...
STUDY OF ENDOTHELIAL DYSFUNCTION IN TYPE 1 DIABETES MELLITUS USING DOPPLER ULTRASOUND.
Introduction:Microvascular diabetic complications are the most common causes of morbidity and mortality in patients with type 1 DM. The main etiology for mortality and a great percent of morbidity in patients with diabet...
RELATIONSHIP BETWEEN RED CELL DISTRIBUTION WIDTH AND CLINICAL STROKE SCORING SYSTEMS IN ACUTE ISCHEMIC STROKE.
Red cell distribution width (RDW) is a hematological parameter routinely obtained as a part of Complete blood count. Recently RDW has emerged as a potential independent predictor of clinical outcome in patients with esta...
ERGONOMICS FACTORS, MENTAL AND PHYSICAL LOADS AMONG HEALTH-CARE WORKERS.
Organizational ergonomics aspects, physical and mental task demands are considerable safety factors that can lead to poor performance and injuries in particular, health-care sector. This study aimed at identifying the ma...