Effect of Pogostemon Parviflavus Leaves Extracts against Candida Albicans.
Journal Title: International Journal of Dental Science and Innovative Research (IJDSIR) - Year 2019, Vol 2, Issue 3
Abstract
Introduction: Oral Carcinoma (SCC) is the result of a multistage process from normal to dysplastic lesions. A premalignant or precancerous lesion is defined by the World Health Organization as a morphologically altered tissue in which cancer is more likely to occur. In oral cavity, the oral micro flora may be subsequently replaced by potentially pathogenic microorganisms, such as Candida sp., (from 72% to 92%). Material and Method: Fresh and mature leaves of plantsPogostemon parviflorus were collected. Exactly 0.2g of crude DMSO (Dimethyl sulfoxide) extract of Pogostemon parviflorus leaves was dissolved in 2ml DMSO (Dimethyl sulfoxide) to get 100mg/ml concentration. Results:Pogostemon parviflorus leaves extracts in DMSO solution gives inhibitory effect against clinically isolated Candida albicans spp.Conclusion: To fight against fungal infections antifungaldrugs are used as an important weapon which greatly benefited the health related quality of human life since their introduction but over the past few decades these health benefits are under threats as many commonly used antibiotics have now become less effective due to emergence of drug resistivity.
Authors and Affiliations
Dr. Shaista Suhail
Keywords
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