Effect of preloading of intravenous crystalloid fluids on postoperative nausea and vomiting
Journal Title: International Journal of Medical Science and Innovative Research (IJMSIR) - Year 2017, Vol 2, Issue 5
Abstract
Introduction: Postoperative nausea and vomiting (PONV) are among the most common adverse events following surgery. Preoperative fasting combined with anesthesia & surgical losses results in state of transient & relative gut ischemia through mesenteric hypoperfusion, which has been identified as one of the factors responsible for PONV. Methodology: A Total of 120 patients undergoing different kinds of surgeries under General Anesthesia were randomly allotted to 4 groups of 30 patients each to receive 5ml/kg, 10ml/kg, 20ml/kg IV preloading of crystalloid fluids (RL) 30 minutes before induction & No fluids in control group (Group C) to compare their effect on PONV. Result: Incidence of Nausea was highest in Group 5 and it was lowest in group 10 (p value <0.05). Comparison of Nausea between Group 10 & Group 20 shows no statistically significant difference (P value >0.05). Similarly Comparison between Group 5 & Group C shows no significant statistical difference (p value is >0.05). We had observed that incidence of Vomiting & requirement of rescue antiemetic drug was lowest in Group 10 followed by Group 20 & than Group 5 (p value <0.05). No. of patients who required treatment for vomiting (VAS PONV Score >5) was lowest in Group 10(n-5) followed by Group 20(n-7). It was highest in Group C (n-28). Conclusion: Preoperative preloading of IV fluid therapy in the form of Ringer’s lactate 10mg/kg is a simple, cost effective and safe means to reduce the occurrence of postoperative nausea and vomiting.
Authors and Affiliations
Dr. Devendra kumar J Prajapati
Keywords
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