Effect of Testosterone and Estrogen Ratio - An indicator of Benign Prostatic Hyperplasia (BPH)
Journal Title: Indian Journal of Clinical Anatomy and Physiology - Year 2016, Vol 3, Issue 2
Abstract
Background: Benign prostatic hyperplasia (BPH) is one of the most common disease and major cause of morbidity in elderly men. Prostatomegaly often used interchangeably with BPH, is a prominent feature of the disease. Although sex steroid hormones play a vital role in prostate growth, their clinical significance is not completely clear. The phenomenon may be correlated with changes of sex hormone in serum of elderly population. Hence, the objective of this study was to study the roles of serum hormones levels – Testosterone (T) and Estradiol (E2) in elderly patients aged 60-75 years who are diagnosed with benign prostatic hyperplasia (BPH) and to understand the correlation between T/E2 ratio over age as markers of prostate disease. Methods: To conduct this case control study, a population of 30 patients with benign prostatic hyperplasia (BPH) had been selected and 30 well-matched males without BPH as a control group. Result: Testosterone level declined with age, but serum estrogens level remains unaltered so estrogen may be involved in the development of BPH. Conclusion: The present study suggests that testosterone estrogen ratio can be an indicator of BPH in patients above 45 years of age.
Authors and Affiliations
Qhurrathul Ain Sayeed, Farisa Khatoon, Farah Bahmed, Maria Kaleem
Keywords
Related Articles
- EP ID EP242109
- DOI -
- Views 102
- Downloads 0
Evaluation of pulmonary functions in alternate fuel users
Introduction Indoor air pollution is present in rural areas due to usage of biomass fuel like wood dung or crop residues for cooking The rural women are exposed to the smoke produced by combustion of these materials whic...
A study of magnesium supplementation on sensory nerve conduction velocity (N.C.V) in patients of diabetic neuropathy
Introduction Globally diabetes is the leading known cause of neuropathy In type 2 diabetes mellitus neuropathy being the most common complication contributes to majority of morbidity and mortality in such patients Hyperg...
Effect of isometric handgrip test on heart rate variability in primary open angle glaucoma
Introduction: Open angle glaucoma is a chronic, slowly progressive optic neuropathy characterised by progressive visual field loss. At systemic level; hypertension, hypotension leading to reduced ocular blood flow (OBF),...
Evaluation of day time sleepiness using Epworth sleepiness score among medical students
Introduction Physiologic and cognitive function in humans vary considerably with the circadian rhythm which also regulates the sleep cycle Sleep is an active repetitive and reversible behavior serving several different p...
A study of range of motion of neck in adult population of Western Rajasthan
Introduction: The amount of motion available at a joint is knowns range of motion. Background: The purpose of the study was to predispose the effect of age and gender on movements of cervical spine in 100 normal subjects...