Effect of two different doses of Dexmedetomidine on hemodynamic responses during tracheal extubation
Journal Title: Medpulse International Journal of Anesthesiology - Year 2018, Vol 8, Issue 3
Abstract
Background: Haemodynamic responses to tracheal extubation have always been of importance to the anaesthesiologist.Different concentrations of dexmedetomidine ranging from 0.25 µg/kg to 1.0 µg/kg intravenously as a bolus, have been studied for attenuation of pressor responses to extubation and intubation. Aim: To study the effects of two different doses of dexmedetomidine on hemodynamic responses during tracheal extubation. Material and Methods: A total of 66 patients undergoing surgery under general Anaesthesia in our hospital were randomly divided into 2 groups: Group-D1: Dexmedetomidine (0.25 µg/kg) group –33 patients; Group-D2: Dexmedetomidine (0.5 µg/kg) group – 33 patients. Results: The heart rate was significantly lower in D2 group at 10 minutes after starting of study drug, during extubation and till 15 minutes after extubation (p<0.05).The SBP and DBP was significantly lower in D2 group during extubation and till 15 minutes after extubation (p<0.05). Conclusion: Dexmedetomidine in 0.5 mcg/kg dose is optimum to attenuate the extubation response as compared to low dose i.e., 0.25 mcg/kg.
Authors and Affiliations
Pradeep Shivaji Raut, Ghanshyam Jadhav
Keywords
Related Articles
- EP ID EP453352
- DOI 10.26611/1015839
- Views 150
- Downloads 0
Study of comparative evaluation of bupivacaine and bupivacaine with dexmedetomidine in subarachnoid block for below umbilical surgeries
Background: Spinal anaesthesia is the most preferred regional anaesthesia technique as it is easy to perform, economical and produces rapid onset of anaesthesia and complete muscle relaxation. Dexmedetomidine, an α2 agon...
Analysis of anterior soft tissue thickness using ultrasonogram, body mass index and neck circumference in predicting difficult intubation
Background: Difficult endotracheal intubation under general anesthesia can cause intubation delay or failure, which can bring on fatal results. Though there are various methods to predict the airway difficulty, none of t...
Effect of provider communication on perception of pain during intravenous cannulation: A double blinded randomized controlled trail
Background: Anaesthesiologists utilize communication skills in their day to day practice in order to reduce the pain perception of patients during invasive procedures like intravenous cannulation. Our study aimed to know...
Comparative study of intrathecal dexmedetomidine and intrathecal magnesium sulphate used as adjuvants with hyperbaric bupivacaine in lower abdominal and lower limb surgeries
Background: Subarachnoid block is the most commonly used regional anesthetic technique for lower abdominal and lower limb surgeries. Intrathecal adjuvants have gained popularity with the aim of prolonging the duration an...
Anaesthetic management of a patient with sick sinus syndrome for vaginal hysterectomy
Background: Sick sinus syndrome is a generalised abnormality of cardiac impulse formation that may be caused either by an intrinsic disease of the sinus node, which makes it unable to perform its pacemaking function, or...