Effect of two hours formaldehyde exposure on lung functions in the 1st MBBS medical students
Journal Title: Applied Physiology and Anatomy Digest - Year 2018, Vol 3, Issue 2
Abstract
Introduction: First year MBBS students are exposed to the formaldehyde gas during their Anatomy dissection classes almost every day. Effect of acute exposure of formaldehyde on the lung functions is not well documented in the available literature. So this study was planned to study effect of two hours of formaldehyde exposure on first year medical students. Materials and Methods: 80 first MBBS students were enrolled in the study, after application of inclusion and exclusion criteria. Their anthropometric parameters were recorded by standardized methods and BMI was calculated using Quetlet’s Index. FVC maneuver was performed in the students before and after the formaldehyde exposure for two hours during their anatomy dissection classes. Data was analyzed using paired t-test. Results: The FVC and FEV1 were decreased after the exposure to formalin but the difference between the values was statistically non-significant (p>0.05). Moreover the values of the FVC/FEV1, FEF 25-75, PEFR were also decreased after exposure to formalin and the difference between them was statistically significant (p<0.05). Conclusion: Two hour exposure to formaldehyde in the anatomy dissection hall causes decrease in the lung functions. The results indicate that there Might be mid airway constriction which leads to decreased FEF 25-75, PEFR. The decreased lung functions are indicative of the respiratory derangement due to acute effect of formaldehyde
Authors and Affiliations
Lad Umesh
Keywords
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