Effect on Quality of Life of a Lentinus edodes mycelia-enriched diet (L･E･M®) in patients with terminal cancer
Journal Title: Journal of Analytical Bio-Science - Year 2013, Vol 36, Issue 2
Abstract
Purpose: It is important to offer the highest possible quality of life (QOL) for terminal cancer patients in palliative medicine. It was examined whether Lentinus edodes mycelia (L･E･M®) -containing diet (CORELEM®) was effective in improving the QOL for terminal cancer patients. Methods: Efficiency for QOL of L･E･M® was examined by repeated oral administration in a dosage equivalent to 1,000-1,500 mg L･E･M®/day to 105 terminal cancer patients for 4 weeks with placebo as a control using the double-blind parallel-group comparison test. Results: The CORELEM® group showed a significant improvement in clinical conditions of pain, depression, insomnia, and mouth dryness compared to the placebo group. Moreover, both groups showed no serious adverse events during diet ingestion. Conclusion: It was suggested that CORELEM® is effective in improving QOL and safely ingestible for terminal cancer patients.
Authors and Affiliations
Takashi Higashiguchi
Keywords
Related Articles
- EP ID EP98538
- DOI -
- Views 89
- Downloads 0
The usefulness of validation support reagent in a routine test
In a clinical test, validation is indispensable in order to guarantee the reliability of measurement values and the most fundamental point to be checked. A "Guideline for the validation of quantitative measurement metho...
A study on simultaneous measurement method for both platelets and fragmented red cells using flow-cytometric immunoplatelet count
Simultaneous measurement of both platelets and fragmented red cells (FRCs) using the flow-cytometric immunoplatelet (CD41/CD61) count was attempted. FRCs were prepared artificially by heating. The ICSH/ISLH immunoplatele...
Study of oxidative damage by myeloperoxidase derived reactive oxygen
Neutrophils enhance the production of reactive oxygen as a result of the priming reaction by various cytokines. However, the relationship is still unknown between the priming reaction and releasing of myeloperoxidase (MP...
Development of assays for measuring HBV- and HCV-related markers
Several decades have passed since HBV and HCV were identified, and many assays for measuring HBV/HCV-related markers have annually developed. These assays have contributed to the development of kinetic analysis, diagnosi...
Folate Up-to-date
Folate is one of essential vitamin, and vital to normal cell growth and DNA synthesis. Folate deficiencies lead to megaloblastic anemia and ultimately to severe neurological problems. Folate concentration can be differen...