Effect on the biochemical and hematological parameters on Rasa Mezhugu in Freund’s adjuvant-induced arthritis rats
Journal Title: World Journal of Pharmaceutical Sciences - Year 2016, Vol 4, Issue 10
Abstract
Rheumatoid Arthritis (RA) is a chronic, destructive inflammatory poly-articular joint and systemic autoimmune disease. It typically results in warm, swollen, and painful joints, stiffness often worsen following rest. The goal of treatment is to reduce pain, decrease inflammation, and improve a person's overall functioning. In spite of tremendous development in the field of synthetic drugs during recent years, the side effects could not be avoided. Hence the current research focus is to develop less toxic drugs as early as feasible in the disease process. A 90 day old Wistar male rat was used for the research and was divided in to four groups treated with Saline, Palm Jaggary, Rasa Mezhugu and Indomethacin. Evaluation of anti-arthritic potency, by body weight, biochemical and hematological analysis were analyzed. Rasa Mezhugu treatment rats have significantly reduces the Arthritis effect induced by complete Freund's adjuvant (CFA)-induced arthritic rat.
Authors and Affiliations
Dr. Nandhagopal K
Keywords
Related Articles
- EP ID EP203130
- DOI -
- Views 61
- Downloads 0
Synthesis of antimicrobial active benzimidazole-2-thioate derivatives of 2-mercaptobenzimidazole
Synthesis of antimicrobial active benzimidazole-2-thioate derivatives of 2-mercaptobenzimidazoleA facile, green, efficient and one pot synthetic method for biological active benzimidazole-2-thioate derivatives comprising...
A study on demographic profile and cell proliferative activity in Oral Lichen Planus (OLP) and Oral Epithelial Dysplasia (OED) using Ki-67 marker
Background: In oral lichen planus (OLP), destruction of the basal cell layer, which is one of the characteristic histological features, is seen and many changes in cell proliferation, cell repair and cell death occur in...
Role of biotechnology in industry and health care
Application of the field of Biotechnology has now become an integral part of every industrial organization involving diverse types of various industries, pharmaceuticals, agriculture, dairy, medicine, molecular genetics,...
Bioactive compounds from Malva rotundifolia L.
Eight compounds were isolated for the first time from the methanolic extract of Malva rotundifolia L. Based on spectroscopic data and mass techniques, the structures of these compounds were identified as palmitic acid (1...
Stability indicating RP-HPLC method development and validation of metformin hydrochloride and glimepiride in bulk and pharmaceutical dosage form
A stability indicating RP-HPLC method was developed and validated for the determination of Metformin HCl and Glimepiride in tablet dosage form. The method was carried out using Agilent C18 column (250 mm×4.6 mm, 5 μ) wit...