Effectiveness of inverted internal limiting membrane flap technique combined with sterile air tamponade surgery on managing idiopathic macular hole

Journal Title: Guoji Yanke Zazhi - Year 2018, Vol 18, Issue 7

Abstract

AIM:To compare the effectiveness of inverted internal limiting membrane flap(ILMF)coverage combined with sterile air tamponade or C<sub>3</sub>F<sub>8</sub>-filled surgery for idiopathic macular hole(IMH). <p>METHODS: In this retrospective study, 165 patients(175 eyes)who underwent pars plana vitrectomy(PPV)combined with inverted ILMF coverage were evaluated. The surgeries were performed by one surgeon at the Renmin Hospital, Wuhan University between January 2014 and June 2017. The patients were divided into sterile air(Group A)and C<sub>3</sub>F<sub>8</sub>-filled(Group B)groups, based on the technique used for intraocular tamponade. With a minimum 3-month follow-up, pre- and post-operative best corrected visual acuity(BCVA), macular hole closure rate, and major postoperative complications were analyzed. <p>RESULTS: Both groups showed significant improvement in visual acuity at 1 and 3mo postoperatively(<i>P</i><0.05). There was no significant difference between the two groups 1mo postoperatively, but the average BCVA in Group A was better than that in Group B at 3mo, to a level of statistical significance(<i>P</i><0.05). The closure rate of macular hole was 97.5% in Group A and 96.8% in Group B, a statistically non-significant difference. There were no statistically significant differences in defect diameters of the inner and outer junctions between the two groups at 1 and 3mo postoperatively(<i>P</i><0.05), but significant differences compared to before surgery in both groups(<i>P</i><0.05). The rate of IOP elevation was 9.5% in Group B, and zero(0)in Group A; this difference was statistically significant(<i>P</i><0.05). <p>CONCLUSION: We postulate that PPV combined with inverted ILM flap is a safe and effective method for surgical management of IMH. Compared to C<sub>3</sub>F<sub>8</sub>-filling, sterile air tamponade can avoid IOP elevation; it may replace C<sub>3</sub>F<sub>8</sub>-filling in PPV for IMH.

Authors and Affiliations

Tao He

Keywords

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  • EP ID EP553710
  • DOI 10.3980/j.issn.1672-5123.2018.7.33
  • Views 95
  • Downloads 0

How To Cite

Tao He (2018). Effectiveness of inverted internal limiting membrane flap technique combined with sterile air tamponade surgery on managing idiopathic macular hole. Guoji Yanke Zazhi, 18(7), -. https://europub.co.uk/articles/-A-553710