Mechanism of TUDCA for retinitis pigmentosa
Journal Title: Guoji Yanke Zazhi - Year 2018, Vol 18, Issue 8
Abstract
Tauroursodeoxycholic acid(TUDCA)is formed by taurine conjugated of ursodeoxycholic acid(UDCA). It has the role of neurotrophic factor in anti-inflammatory, anti-apoptosis and reducing the activation of microglial cells. These effects may be one of the most critical of all pathological stages of retinitis pigmentosa. Preclinical trials have shown that TUDCA had potential therapeutic value for retinal degeneration disease. This article discusses how TUDCA can slow down the process of retinal degeneration.
Authors and Affiliations
Yan Liu
Keywords
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- EP ID EP547950
- DOI 10.3980/j.issn.1672-5123.2018.8.10
- Views 127
- Downloads 0
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